Research Articles
ResearchMarch 21, 2026

Growth Hormone Secretagogues: CJC-1295 and Ipamorelin Research

An overview of research into CJC-1295 and Ipamorelin as growth hormone secretagogues, including their mechanisms and current scientific understanding.

Growth Hormone Secretagogues

Growth hormone secretagogues (GHS) are compounds that stimulate the secretion of growth hormone (GH) from the pituitary gland. CJC-1295 and Ipamorelin represent two distinct classes of GHS that are frequently studied together.

CJC-1295

CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH). It is modified with Drug Affinity Complex (DAC) technology to extend its half-life.

Key Properties:

  • Acts on GHRH receptors in the pituitary
  • Extended half-life compared to native GHRH
  • Promotes pulsatile GH release

Ipamorelin

Ipamorelin is a selective growth hormone secretagogue receptor (GHSR) agonist. It belongs to the ghrelin mimetic class of peptides.

Key Properties:

  • Selective GH release without significant cortisol or prolactin elevation in studies
  • Pentapeptide structure: Aib-His-D-2-Nal-D-Phe-Lys-NH2
  • Molecular weight: 711.9 g/mol

Research Use Only: These compounds are for laboratory research only and are not approved for human use.

CJC-1295 Ipamorelin growth hormone GHS

Disclaimer: This article is for informational and educational purposes only. It does not constitute medical advice. All research peptides discussed are intended for laboratory use only and are not approved for human consumption.