Research Articles
CognitiveMarch 21, 2026

Selank and Semax: Nootropic Peptides in Neuroscience Research

An exploration of the neuroscience research surrounding Selank and Semax, two peptides studied for their potential cognitive and anxiolytic properties.

Overview

Selank and Semax are synthetic peptides originally developed in Russia that have garnered significant interest in neuroscience research for their potential cognitive and anxiolytic properties.

Selank

Selank is a heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) that is an analog of the immunomodulatory peptide tuftsin.

Research Areas:

  • Anxiolytic effects in animal models
  • Modulation of GABA-A receptor activity
  • Effects on BDNF expression

Semax

Semax is a synthetic peptide derived from ACTH(4-7) with the sequence Met-Glu-His-Phe-Pro-Gly-Pro.

Research Areas:

  • Neuroprotective effects in ischemia models
  • BDNF and NGF upregulation
  • Cognitive enhancement in animal studies

Research Use Only: These peptides are for laboratory research only and have not been approved by the FDA for human use.

Selank Semax nootropic neuroscience BDNF

Disclaimer: This article is for informational and educational purposes only. It does not constitute medical advice. All research peptides discussed are intended for laboratory use only and are not approved for human consumption.